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Abstract : Background: Acute Pancreatitis is one of the most common reasons to visit an ER with wide spectrum of severity. It requires assessment of severity for better management and to avoid complications. Few studies have been done to assess the severity scoring systems in their ability to predict severe acute pancreatitis. Hence, we aim to compare the various scoring systems in order to find out which is the best in predicting the outcome in acute pancreatitis. Method: Demographic, radiographic and laboratory data was collected retrospectively of patients with Acute Pancreatitis who were admitted in district Wenlock hospital, Mangalore between January-June 2022. Modified Atlanta, Ranson, BISAP, Glasgow imrie score of all patients was calculated. and statistically analysed for correlation between each pair of scoring systems. Results: Of 107 patients, Male gender formed 96.3%(103), Females formed 3.7% (4)of the patients suffering from Acute Pancreatitis. Ranson, BISAP and Glasgow score, all three showed a strong association with Modified Atlanta Score according to the Fishers exact test(p0.05). Ranson score with an AUC of 0.881 suggests that a Ranson score of 2 with sensitivity of 90% and specificity of 78.7% was a cut off score in our study in predicting the severity of Acute Pancreatitis. Similarly, a BISAP score close to 2 with AUC of 0.766 was a cut off point in predicting severity with a sensitivity of 70% and specificity of 83.1%. A Glasgow imrie score of 2 was a cut off point with AUC 0.860 in predicting severity of acute pancreatitis with a sensitivity of 80% and specificity of 78.7%. Conclusion: Our study demonstrated that a higher score on these scoring systems correlated with greater severity of the disease. A cut off score of 2 on the Ranson scoring system demonstrated the highest sensitivity of 90% and highest correlation with the modified Atlanta score.